Peptides Discussed on Modern Wisdom’s Biohacking Roundtable #1148
Williamson’s roundtable with physician Gabrielle Lyon, biohacker Ben Greenfield and healthcare entrepreneur Brigham Buhler ranged far beyond peptides. This episode-specific audit covers the peptide and peptide-hormone names that can be verified, while keeping personal routines, commercial claims and regulatory arguments separate from clinical evidence.
Best Peptides, Stem Cells, Testosterone & Exercise Hacks – Biohacking Roundtable – #1148
Guest: Dr. Gabrielle Lyon, Ben Greenfield and Brigham Buhler · Released September 10, 2026
Listen to the official Modern Wisdom episode audioHow this article was verified
Modern Wisdom’s official episode index confirms the exact #1148 title and September 10, 2026 release date. The show-feed description identifies the three roundtable guests, and the complete episode transcript supports the compounds below. The automated transcript renders several names phonetically—including Thymosin Alpha-1, tesamorelin, ipamorelin, Semax and Selank—so a standard name is used only where the surrounding discussion makes the identity clear. No uncertain “G8” identification is included.
Compounds discussed in this episode
Speaker claims below are paraphrases, not endorsements or quotations. Scientific context is separated from the speaker's experience or opinion.
01Thymosin Alpha-1
What the speaker said
Greenfield described keeping Thymosin Alpha-1 available while traveling and associated it with immune support. This was a report about his own routine, not evidence of protection from infection or a recommendation by the panel.
Scientific Context
Thymosin Alpha-1 has been studied as an immune modulator in several disease settings, but it is not FDA-approved in the United States. A travel anecdote cannot establish preventive efficacy, product quality or long-term safety.
Where to buy for laboratory research
Thymosin Alpha-1 at Base Peptides — verified exact-name product page. This editorial listing is not a guest endorsement and is not a recommendation for human use.
02BPC-157
What the speaker said
Greenfield said he keeps BPC-157 for injuries. Later, Buhler cited an industry retrospective analysis during his account of an FDA compounding hearing and emphasized its low reported adverse-event count. Neither a personal use report nor retrospective safety reporting demonstrates that BPC-157 heals an injury.
Scientific Context
The injury literature remains predominantly laboratory and animal research. BPC-157 has no FDA-approved indication, and retrospective reports without a controlled comparison cannot establish efficacy, detect every adverse event or replace prospective safety trials.
Where to buy for laboratory research
BPC-157 at Base Peptides — verified exact-name product page. This editorial listing is not a guest endorsement and is not a recommendation for human use.
03TB-500
What the speaker said
Greenfield grouped TB-500 with BPC-157 as something he keeps for injuries. He reported a use case, but the roundtable did not present a controlled recovery outcome.
Scientific Context
TB-500 is marketed as a thymosin beta-4-related fragment and should not be treated as interchangeable with full-length thymosin beta-4. Human injury-recovery evidence is inadequate, and it is not an FDA-approved treatment.
Where to buy for laboratory research
TB-500 at Base Peptides — verified exact-name product page. This editorial listing is not a guest endorsement and is not a recommendation for human use.
04Tesamorelin
What the speaker said
Greenfield included tesamorelin in a periodic growth-hormone-related routine. Near the end, the panel again named it as one of the newer secretagogue options that displaced older compounds. Those comments were personal and comparative opinions, not evidence for general anti-aging or muscle-building use.
Scientific Context
Tesamorelin is FDA-approved for reducing excess abdominal fat in adults with HIV and lipodystrophy. That narrow indication does not establish benefits for healthy people, general fat loss, longevity or performance.
Where to buy for laboratory research
Tesamorelin at Base Peptides — verified exact-name product page. This editorial listing is not a guest endorsement and is not a recommendation for human use.
05Ipamorelin
What the speaker said
Greenfield named ipamorelin alongside tesamorelin and CJC-1295 in his personal growth-hormone-related routine. The panel later characterized newer secretagogues as preferable to older GHRPs, but did not supply head-to-head clinical results.
Scientific Context
Ipamorelin can stimulate growth-hormone release, but that pharmacologic effect is not proof of better recovery, body composition or lifespan. It is not FDA-approved for those outcomes, and long-term human evidence is limited.
Where to buy for laboratory research
Ipamorelin at Base Peptides — verified exact-name product page. This editorial listing is not a guest endorsement and is not a recommendation for human use.
06CJC-1295
What the speaker said
Greenfield named CJC-1295 as part of the same routine, and Buhler said he uses CJC-related secretagogues after coming off IGF-1 LR3. The speakers did not resolve whether they meant DAC-linked CJC-1295 or a short-acting no-DAC material.
Scientific Context
Molecular form matters because DAC and no-DAC materials have different pharmacokinetics. Early studies show growth-hormone and IGF-1 responses, not established broad wellness, performance or longevity benefits.
Where to buy for laboratory research
No exact product is linked because the episode does not specify DAC versus no-DAC; the verified Base Peptides page is specifically CJC-1295 DAC. No substitute or near-match is linked.
07Semax
What the speaker said
The transcript’s “C-Max” is identifiable as Semax from Greenfield’s description of an intranasal cognitive peptide associated with BDNF. His favorable characterization was a personal impression and mechanistic claim, not a measured cognitive result.
Scientific Context
Semax has preclinical and regional clinical literature, including neurologic settings, but is not FDA-approved. That evidence does not establish routine cognitive enhancement in healthy people.
Where to buy for laboratory research
Semax at Base Peptides — verified exact-name product page. This editorial listing is not a guest endorsement and is not a recommendation for human use.
08Selank
What the speaker said
Greenfield contrasted Selank with Semax and described it as the more calming member of the pair. This was his own shorthand for perceived effects, not a controlled anxiety or sleep finding.
Scientific Context
Selank research is limited and largely regional. It is not FDA-approved, and the available literature does not establish a broadly effective anxiety or sleep treatment.
Where to buy for laboratory research
Selank at Base Peptides — verified exact-name product page. This editorial listing is not a guest endorsement and is not a recommendation for human use.
09IGF-1 LR3
What the speaker said
Buhler said IGF-1 LR3 was the principal addition to Greenfield’s list and described himself as a strong proponent. He claimed it retained desired growth-hormone-related effects with fewer drawbacks. Those are attributed opinions and personal use reports; the episode did not provide comparative trial evidence.
Scientific Context
IGF-1 LR3 is a long-acting research analogue, not an FDA-approved muscle-building or anti-aging treatment. Controlled human efficacy and long-term safety data for those uses are inadequate, with unresolved risks related to glucose regulation and growth signaling.
Where to buy for laboratory research
IGF1 LR3 at Base Peptides — verified exact-name product page. This editorial listing is not a guest endorsement and is not a recommendation for human use.
10Unspecified GLP-1 receptor agonist
What the speaker said
Lyon and Greenfield each described occasional personal use of a low amount of an unnamed GLP-1 drug, while Buhler discussed reports from his clinic population. They speculated about inflammation and food noise and explicitly acknowledged uncertainty. The episode never identifies the active molecule in these personal reports.
Scientific Context
GLP-1 is a drug class and physiologic pathway, not an exact product name. Evidence, indications and risks differ among semaglutide, tirzepatide, liraglutide and other agents; class-level anecdotes cannot be assigned to one compound.
Where to buy for laboratory research
No product is linked because the speakers did not identify the molecule. Linking any specific GLP-1 agonist would be an unsupported substitution. No substitute or near-match is linked.
11Vasoactive intestinal peptide (VIP)
What the speaker said
VIP was mentioned briefly as a nasal peptide sometimes used in a mold-related treatment context. The panel did not report a controlled outcome, and the surrounding exchange focused on an over-the-counter alternative rather than VIP itself.
Scientific Context
Vasoactive intestinal peptide is an endogenous signaling peptide with broad physiologic effects. A passing clinical anecdote does not establish a standard treatment for mold-related illness, and formulation-specific evidence would be required.
Where to buy for laboratory research
No live exact VIP product page was verified at Base Peptides or Peptide Stock at review time. No substitute or near-match is linked.
12Human chorionic gonadotropin (hCG)
What the speaker said
Buhler referred to hCG while describing care he received years earlier for body composition and hormone-related goals. This was a retrospective personal account and included other interventions, so no effect can be attributed to hCG alone.
Scientific Context
hCG is an FDA-approved prescription glycoprotein hormone for specific reproductive indications. That does not establish body-composition or general optimization claims outside labeled medical care.
Where to buy for laboratory research
HCG at Base Peptides — verified exact-name product page. This editorial listing is not a guest endorsement and is not a recommendation for human use.
13GHRP-2
What the speaker said
Williamson asked what had happened to GHRP-2 while recalling older growth-hormone secretagogues. The panel’s response was that newer options had largely displaced them, with appetite effects discussed as a drawback. The exchange was recollection, not a comparative trial.
Scientific Context
GHRP-2 is a ghrelin-receptor agonist that can provoke growth-hormone release and can affect appetite and other hormones. It is not FDA-approved for physique, recovery or longevity uses.
Where to buy for laboratory research
GHRP-2 at Base Peptides — verified exact-name product page. This editorial listing is not a guest endorsement and is not a recommendation for human use.
14GHRP-6
What the speaker said
Williamson paired GHRP-6 with GHRP-2 in the same retrospective question. Speakers recalled intense hunger and said the older secretagogues had fallen out of favor; that does not quantify comparative efficacy or safety.
Scientific Context
GHRP-6 activates the ghrelin receptor and is known experimentally for growth-hormone and appetite effects. It lacks an FDA-approved performance or anti-aging indication and robust long-term outcome evidence.
Where to buy for laboratory research
GHRP-6 at Base Peptides — verified exact-name product page. This editorial listing is not a guest endorsement and is not a recommendation for human use.
15Modified GRF (1-29)
What the speaker said
Williamson also named modified GRF while asking about the older secretagogue combinations he remembered. The panel did not distinguish a formulation, report an outcome or present evidence specific to modified GRF.
Scientific Context
Modified GRF (1-29) is a short-acting GHRH analogue often discussed under inconsistent marketplace naming. Product identity and molecular form must be established before evidence can be matched.
Where to buy for laboratory research
No live exact Modified GRF (1-29) product page was verified at Base Peptides or Peptide Stock at review time. No substitute or near-match is linked.
16Ozempic (semaglutide)
What the speaker said
Williamson used Ozempic by name when asking whether testosterone replacement and GLP-1 treatment can become pharmacologic answers to problems that lifestyle might partly address. It was a framing question, not a personal outcome or supplier recommendation.
Scientific Context
Ozempic is FDA-approved semaglutide for specified type 2 diabetes and cardiovascular-risk indications. Its regulated prescription labeling cannot be transferred to an online research vial, and appropriate use is individualized medical care.
Where to buy for laboratory research
No laboratory product is linked because the speaker named the regulated prescription brand Ozempic; a research listing must not be presented as that product. No substitute or near-match is linked.
Sources and limitations
- Modern Wisdom official episode index — primary show source for the exact #1148 title, release date and episode audio listing
- Modern Wisdom #1148 transcript — complete searchable transcript and show-feed description used to verify guests and named compounds; automated spellings were checked in context
- FDA Egrifta SV prescribing information — approved tesamorelin indication and product-specific safety context
- PubMed review of BPC-157 soft-tissue research — peer-reviewed overview illustrating the predominantly preclinical injury evidence
- FDA: unapproved drugs — regulatory context for compounds without an approved indication
Research and educational use only. Most compounds discussed here are not FDA-approved to treat injury, improve performance, or extend lifespan. Laboratory supplier links are editorial references only. Nothing here is medical advice, a dosing guide, or a recommendation for human use.