Research LibraryPopular Peptide Research Dosing Protocols
    Evidence & Protocols

    Popular Peptide Research Dosing Protocols

    An exhaustive, source-controlled index of all 59 current database entries, organized by intended research area. It reports 21 historically published study regimens and explicitly marks 38 entries without a verifiable regimen rather than repeating vendor schedules.

    Key Mechanisms

    Primary-publication screeningSpecies and route contextHistorical human study factsPK and toxicology translation limits

    Research Use Only

    For educational and laboratory-reference purposes only. This is a source-controlled index of historical study facts, not medical advice, a prescription, or an administration guide. The database includes approved drugs, non-peptide compounds, mixtures, and investigational entries; regulatory status is compound- and indication-specific. Research products are not necessarily approved, sterile, accurately labeled, or suitable for human use.

    Quick Facts

    Peptide namePopular Peptide Research Dosing Protocols
    Research categoryEvidence & Protocols
    Primary research interestPublished study regimens, species, routes, durations, indications, and evidence limitations across the complete database

    Scope, coverage, and source-control method

    This article covers every one of the 59 entries currently exported by the Peptide Basics database. “Peptide” is used as the database's broad research-library label: the list also contains approved drugs, non-peptide small molecules, SARMs, coenzyme mixtures, and polypeptide preparations. That distinction matters when interpreting evidence and regulatory status.

    The database's consumer-facing dosage fields are not reproduced as evidence. Each historical regimen in the tables was accepted only when a primary publication, ClinicalTrials.gov record, or FDA label supplied enough detail to identify the species or study population, route, amount, duration, and research indication. The remaining entries say “no published regimen reported here.” That is an evidence finding—not proof that no paper exists anywhere—and it is preferable to filling a gap with an estimated schedule.

    Historical study facts, not dosing instructions

    Amounts and schedules below describe what a named study or label reported. They are not prescriptions, recommendations, stacking or cycling instructions, or instructions for handling a research product. Do not infer a human amount from an animal experiment or combine entries because they share an intended-research category.

    Coverage checkCountInterpretation
    Current database entries59Every entry is rendered exactly once in the research-group tables
    Entries with a cited regimen21A primary paper, registry, or label reports enough protocol detail
    Entries without a verifiable regimen38Explicitly marked; no estimated human or animal protocol is supplied
    Coverage accounting is generated from the live database array.

    How to read a research regimen

    1. Start with the species or population. A mouse, rat, macaque, healthy volunteer, and patient cohort answer different questions.
    2. Separate pharmacokinetic or pharmacodynamic challenges from treatment studies. A single intravenous secretagogue challenge is not a chronic body-composition protocol.
    3. Read the route and formulation exactly as reported. DAC and no-DAC CJC-1295, native GLP-2 and glepaglutide, and TB-500 and full-length thymosin beta-4 are not interchangeable.
    4. Treat duration as part of the regimen. A 28-day trial, a 72-week obesity trial, and a single-dose IVF trigger cannot be collapsed into a generic cycle.
    5. Use the limitation column as part of the result. A statistically positive endpoint in one population does not establish safety, efficacy, or regulatory status in another.

    Several entries are not peptides at all. Tesofensine, MK-677, MK-2866, RAD-140, SLU-PP-332, CMS-121, 5-Amino-1MQ, and BAM-15 are small molecules or SARMs; NAD+ is a coenzyme, whereas glutathione is an endogenous tripeptide. Cerebrolysin and Cortexin are mixtures. Their inclusion reflects the current database, not a claim that they share peptide pharmacology.

    Weight and metabolic research

    This group includes approved incretin drugs, investigational agonists, small molecules, and preclinical metabolic compounds. The table preserves the species, route, duration, and indication of the cited work; it does not turn a trial arm into a recommendation.

    Database entrySpecies or populationRoute and historical study regimenDurationIndication or research questionEvidence limitationPrimary source
    SemaglutideAdults with overweight or obesity without diabetes (n=1,961)Subcutaneous once weekly, escalated to a 2.4 mg target dose68 weeks, including the study escalation periodWeight management with lifestyle interventionA controlled trial in a defined population; the result does not validate unapproved formulations or individualized schedules.STEP 1, PubMed 33567185
    TirzepatideAdults with obesity without diabetes (n=2,539)Subcutaneous 5, 10, or 15 mg once weekly, with a 20-week escalation period72 weeksWeight management with lifestyle interventionPhase 3 results are population- and titration-specific; tirzepatide is a dual agonist, not a proxy for other entries.SURMOUNT-1, PubMed 35658024
    RetatrutideAdults with obesity (phase 2 trial)Subcutaneous once weekly: 1, 4, 8, or 12 mg arms; higher arms began at 2 or 4 mg and escalated every 4 weeks48 weeksWeight management researchInvestigational triple agonist; phase 2 findings do not establish an approved regimen or long-term safety.Retatrutide phase 2, PubMed 37366315
    AOD 9604Obese Zucker ratsOral AOD-9604 500 micrograms/kg once daily19 daysBody-weight gain and adipose-tissue lipolysis researchRat study; this amount is not a human dose, and later human development does not validate an online schedule.AOD-9604 metabolic study, PubMed 11146367
    TesamorelinAdults with HIV-associated lipodystrophy and excess abdominal fatSubcutaneous 2 mg once daily in the pivotal study program26 weeks in the cited trial; longer follow-up was separately studiedReduction of visceral adipose tissue in HIV-associated lipodystrophyThe study population and formulation matter. The current EGRIFTA SV label uses a 1.4 mg daily dose from a 2 mg/vial formulation, whereas the cited pivotal trial used 2 mg daily; neither is a protocol for research products.Falutz et al., PubMed 18057338 and FDA EGRIFTA SV label
    TesofensineAdults with obesity, BMI 30 to 40 kg/m² (n=203)Oral 0.25, 0.5, or 1.0 mg once daily after a 2-week run-in24 weeksWeight-loss research with an energy-restricted dietTesofensine is a small molecule, not a peptide; cardiovascular and central-nervous-system effects limit generalization.Astrup et al., PubMed 18950853
    SLU-PP-332No verifiable human protocol identifiedNo human regimen reported hereNot establishedERR-alpha metabolic and exercise-mimetic researchAn early small-molecule research compound; the database entry must not be read as a human protocol.No verified human protocol located in the reviewed primary sources
    5-Amino-1MQNo verifiable human protocol identifiedNo human regimen reported hereNot establishedNNMT-inhibition and metabolic researchPreclinical NNMT-inhibition findings do not establish a human amount, route, duration, or safety profile.No verified human protocol located in the reviewed primary sources
    CagrilintideAdults with overweight or obesitySubcutaneous self-injection once weekly at 0.3, 0.6, 1.2, 2.4, or 4.5 mg26-week treatment period, with up to 6 weeks of escalation, followed by 6 weeks of follow-upWeight management researchDose-finding phase 2 study; investigational amylin analogue, and the trial schedule is not a general recommendation.Lau et al., PubMed 34798060
    AdipotideSpontaneously obese rhesus macaques; separate GLP safety cohortsSubcutaneous 0.43 mg/kg once daily in the fixed-dose efficacy study; 0.25, 0.43, and 0.75 mg/kg were used in safety cohorts28 consecutive days, followed by a 28-day recovery periodWhite-fat targeting, weight, and insulin-resistance researchNonhuman-primate study with dose-dependent, reversible renal findings; no human protocol or conversion is established.Barnhart et al., PubMed 22072637
    BAM 15No verifiable human protocol identifiedNo human regimen reported hereNot establishedMitochondrial uncoupling and energy-expenditure researchPreclinical uncoupler data carry substantial translation and toxicology uncertainty; no human schedule was accepted.No verified human protocol located in the reviewed primary sources
    11 database entries classified under weight and metabolic research.

    Growth-hormone, muscle, and body-composition research

    Growth-hormone secretagogues, SARMs, IGF analogues, and myostatin-related compounds are often grouped together in online schedules even though their chemistry, receptors, and evidence differ substantially.

    Database entrySpecies or populationRoute and historical study regimenDurationIndication or research questionEvidence limitationPrimary source
    CJC-1295 (No DAC)Healthy adults aged 21–61 yearsSubcutaneous CJC-1295 with DAC; ascending single- and repeat-dose studies included reported doses of 30 or 60 micrograms/kg28- and 49-day study designs; repeat administrations were weekly or biweeklyGrowth-hormone and IGF-1 pharmacologyThe published work concerns the DAC form; it cannot be transferred to no-DAC/Mod GRF products or combined schedules.Teichman et al., PubMed 16352683
    IpamorelinNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    IGF-1 LR3No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    GHRP-2No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    GHRP-6No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    SermorelinNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    MK-677 (Ibutamoren)Healthy adults aged 64–81 years (n=32)Oral placebo or 2, 10, or 25 mg once dailyTwo separate study periods of 14 and 28 daysGrowth-hormone and IGF-1 axis researchIbutamoren is a non-peptide secretagogue; the short endocrine study did not establish a muscle, fat-loss, or longevity treatment.Chapman et al., PubMed 8954023
    MK-2866 (Ostarine)Healthy older men and postmenopausal womenOral placebo, 1 mg, or 3 mg once daily12 weeksLean body mass and physical-function researchEnobosarm/Ostarine is a non-peptide investigational SARM; this phase 2 population and duration do not establish broader safety.Dalton et al., PubMed 22031847
    RAD 140 (Testolone)No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    HexarelinHealthy adult men (n=12)Single intravenous boluses of 0.5, 1, and 2 micrograms/kg in a rising-dose designSingle-dose endocrine challengeGrowth-hormone secretagogue pharmacologyAcute GH-response study, not a chronic body-composition protocol; route and population are not interchangeable with database schedules.Imbimbo et al., PubMed 7957536
    Follistatin-344No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    11 database entries classified under growth-hormone, muscle, and body-composition research.

    Tissue repair, gut, and immune research

    Repair and immune claims span animal injury models, barrier biology, and disease-specific human trials. A topical, oral, or injected study route is listed only when a source reported it.

    Database entrySpecies or populationRoute and historical study regimenDurationIndication or research questionEvidence limitationPrimary source
    BPC-157Rats with transected Achilles tendons or medial collateral ligamentsAcross the cited rat studies: intraperitoneal 10 micrograms/kg or 10 nanograms/kg once daily (the MCL study); the Achilles study also tested 10 picograms/kg, while the MCL study included local 1 microgram/g cream and drinking water at 0.16 microgram/mLFrom 30 minutes after surgery until 24 hours before sacrifice; study-specificTendon and ligament healingPreclinical injury models; no verified human therapeutic regimen and no animal-to-human conversion is appropriate.Staresinic et al., PubMed 14554208 and Cerovecki et al., PubMed 20225319
    TB-500No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    Thymosin Alpha-1No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    KPVNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    ThymulinNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    GlutathioneNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    LL-37No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    Larazotide AcetateAdults with celiac disease and persistent symptoms despite a gluten-free diet (n=342)Oral 0.5, 1, or 2 mg three times daily, 15 minutes before meals12 weeks of treatment, preceded and followed by 4-week placebo phasesCeliac-symptom and intestinal-barrier researchThe 0.5 mg group met the primary endpoint while higher doses did not; this is an investigational, disease-specific trial.Leffler et al., PubMed 25683116
    GLP-2 (Glepaglutide)Adults with short bowel syndrome and high stool output in a glepaglutide trialSubcutaneous glepaglutide (a long-acting GLP-2 analogue), 0.1, 1, or 10 mg once dailyThree-week treatment periods in a randomized crossover design, separated by 4–8-week washoutsIntestinal adaptation and short-bowel-syndrome researchThe cited study tested glepaglutide, not native GLP-2; its regimen must not be transferred to native GLP-2 or another analogue.Naimi et al., PubMed 30880176
    9 database entries classified under tissue repair, gut, and immune research.

    Cognition, sleep, and neuroprotection research

    This category contains several mixtures and small molecules as well as peptides. A database label such as “nootropic” is not evidence of a validated human cognitive protocol.

    Database entrySpecies or populationRoute and historical study regimenDurationIndication or research questionEvidence limitationPrimary source
    PinealonNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    PE-22-28No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    P-21No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    SelankNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    SemaxNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    DihexaNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    9-ME-BCNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    ARA 290Adults with type 2 diabetes and small-fiber neuropathySubcutaneous ARA-290 4 mg once daily28 days, with an additional 28-day observation periodNeuropathic symptoms and metabolic-control researchSmall, indication-specific human trial; ARA-290 remains investigational and the observation period is not continued treatment.Dahan et al., PubMed 25387363
    CerebrolysinNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    CMS 121No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    DSIP (Delta Sleep-Inducing Peptide)No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    VIP (Vasoactive Intestinal Peptide)No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    CortexinNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    13 database entries classified under cognition, sleep, and neuroprotection research.

    Longevity and mitochondrial research

    Longevity is an intended research theme, not a clinical indication. The strongest rows below are still either indication-specific human trials or tightly bounded animal experiments.

    Database entrySpecies or populationRoute and historical study regimenDurationIndication or research questionEvidence limitationPrimary source
    EpitalonNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    NAD+No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    SS-31 (Elamipretide)Adults with genetically confirmed primary mitochondrial myopathySubcutaneous elamipretide 40 mg once daily in MMPOWER-324 weeksPrimary mitochondrial myopathy; six-minute-walk and fatigue outcomesMMPOWER-3 did not improve six-minute-walk distance or fatigue versus placebo. As of 2026, elamipretide (Forzinity) has FDA accelerated approval only to improve muscle strength in adults and pediatric patients with Barth syndrome weighing at least 30 kg; that label and formulation do not establish a PMM or research-product protocol.MMPOWER-3, PMC 10382259 and Forzinity FDA label
    MOTS-CYoung CD-1 and C57BL/6J mice, plus middle-aged and old C57BL/6N miceIntraperitoneal MOTS-c: 5 mg/kg/day for 2 weeks in young CD-1 mice; 5 or 15 mg/kg/day in a CD-1 high-fat-diet experiment; 15 mg/kg/day for 2 weeks in C57BL/6J and middle-aged/old C57BL/6N mice; a late-life arm used 15 mg/kg three times weeklyStudy-specific: 2 weeks for the cited daily-dose experiments; one CD-1 high-fat-diet exercise readout followed 10 days of treatment, while the late-life arm was longitudinal intermittent dosingMuscle homeostasis, insulin sensitivity, and exercise-capacity researchMouse study; the amount is not a human dose and the peptide has no validated human protocol.MOTS-c exercise and muscle study, PMC 7817689
    FOXO4-DRINaturally aged male miceIntraperitoneal FOXO4-DRI 5 mg/kg every other day for three administrationsMarkers were assessed 30 days after the dose seriesSenescent-Leydig-cell and testosterone researchAged-mouse senolytic study; no human pharmacokinetics, toxicology, or regulated human regimen exists.Zhang et al., PubMed 31959736
    HumaninNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    6 database entries classified under longevity and mitochondrial research.

    Skin and topical research

    Cosmetic ingredients and matrix peptides are not interchangeable with injectable products. Where a regimen could not be verified in a primary publication, the entry is marked accordingly.

    Database entrySpecies or populationRoute and historical study regimenDurationIndication or research questionEvidence limitationPrimary source
    GHK-CuNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    SNAP-8No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    PAL-AHK (Palmitoyl Tripeptide-1)No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    3 database entries classified under skin and topical research.

    Sexual, reproductive, and hormonal research

    The human studies in this group are narrow—such as IVF trigger research or the approved bremelanotide indication—and should not be generalized to other hormonal goals.

    Database entrySpecies or populationRoute and historical study regimenDurationIndication or research questionEvidence limitationPrimary source
    PT-141Premenopausal women with acquired, generalized HSDDFDA label: subcutaneous bremelanotide 1.75 mg as needed at least 45 minutes before anticipated sexual activity; no more than one dose in 24 hours and eight doses per monthOn-demand use in the approved indication; label does not define a continuous courseAcquired, generalized hypoactive sexual desire disorderBremelanotide is an FDA-approved drug for a defined population; the label is not evidence for PT-141 research products or other indications.Current DailyMed label
    OxytocinNo verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    Melanotan 2No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    KisspeptinWomen undergoing IVF after ovarian stimulationA single subcutaneous kisspeptin-54 injection at 1.6, 3.2, 6.4, or 12.8 nmol/kgSingle trigger; oocytes were retrieved 36 hours laterLH surge and oocyte-maturation researchA specialist IVF trigger study; it does not establish a general hormonal or libido protocol.Kisspeptin-54 IVF study, PubMed 25036713
    4 database entries classified under sexual, reproductive, and hormonal research.

    Other experimental entries

    These entries are retained for database completeness. A name in the database is not evidence that a dose, route, duration, or human indication has been established.

    Database entrySpecies or populationRoute and historical study regimenDurationIndication or research questionEvidence limitationPrimary source
    PNC-27No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    MK-777No verifiable organism-level or human regimen identifiedNo published regimen reported hereNot establishedThe database category is an intended research area, not a demonstrated indicationNo protocol met this article's primary-source standard; vendor schedules and related compounds were excluded.No verified protocol located in the reviewed primary sources
    2 database entries classified under other experimental entries.

    Why animal-to-human translation is not a dose conversion

    An animal amount is not a human starting amount. Species differ in absorption, plasma protein binding, enzymatic cleavage, receptor distribution, immune recognition, renal and hepatic clearance, and disease biology. Even within one species, sex, age, strain, injury model, formulation, assay, and injection site can change exposure. A nominal amount per kilogram therefore cannot be converted operationally into a human schedule by arithmetic.

    Responsible translation requires pharmacokinetics and pharmacodynamics (what exposure occurs and what biological response follows), formulation and bioavailability work, repeat-dose toxicology, immunogenicity assessment, reproductive and genotoxicity work where relevant, and validated analytical methods. A regulated clinical trial then establishes a monitored starting exposure, escalation rules, stopping criteria, adverse-event surveillance, and an indication-specific endpoint. Those safeguards are why the tables preserve study context instead of offering animal-to-human conversions.

    Regulatory status is entry-specific

    This database includes approved drugs and labeled indications alongside investigational compounds and non-peptide research chemicals. A compound may be approved for one indication while remaining investigational for another, as the elamipretide row illustrates. Check the cited label or current FDA source for the specific compound and indication.

    What this index can—and cannot—establish

    • It can document a historical regimen reported in a named study, including its population, route, duration, and research question.
    • It cannot establish that a research-only product has pharmaceutical identity, sterility, potency, or freedom from endotoxin or immunogenicity risk.
    • It cannot turn an approved label into permission to use a different formulation, route, population, or indication.
    • It cannot validate a supplier's schedule, a social-media protocol, a stack, a cycle, or a dose copied from a related molecule.
    • It cannot replace a protocol approved by an institutional review board or animal-care committee, a regulated trial, or qualified clinical and regulatory oversight.

    Research-use boundary

    For educational and laboratory-reference purposes only. Do not use this index as medical advice or as an operational administration guide. Research products may be mislabeled or contaminated, and human investigational use requires appropriate regulatory oversight.

    Frequently Asked Questions

    How many current database entries does this article cover?

    It covers all 59 entries in the current Peptide Basics database. The tables are generated from the database array and each entry is classified into one intended-research group.

    Does every entry have a verified dosing protocol?

    No. 21 entries have a regimen supported here by a primary publication, registry, or FDA label. 38 entries are explicitly marked as having no verifiable protocol under the article's source standard.

    Are the human amounts in this article recommendations?

    No. Human amounts are historical facts from a named trial or label, presented with population, route, and duration. They are not prescriptions, and they do not establish a schedule for a different formulation, indication, or person.

    Can an animal regimen be converted into a human regimen?

    Not by a simple mg/kg calculation. Translation requires pharmacokinetic and pharmacodynamic modeling, formulation and bioavailability work, repeat-dose toxicology, immunogenicity assessment, and regulated clinical-trial oversight.

    Are all entries research-only compounds without FDA approval?

    No. The database includes approved drugs and non-peptide entries as well as investigational compounds. Approval and labeling are compound- and indication-specific; check the cited FDA label or current FDA source rather than applying a blanket status.

    Why does the article sometimes say no verifiable protocol exists?

    Because a database category or vendor schedule is not a verified study regimen. When the reviewed primary literature did not provide enough species or population, route, duration, indication, and amount detail, the article leaves the gap explicit instead of inventing a protocol.

    GLP-1 Receptor Agonist

    Semaglutide

    Semaglutide is a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist studied extensively in clinical research for its association with glycemic regulation, appetite signaling, and body-weight reduction.

    Read profile
    Dual GIP / GLP-1 Receptor Agonist

    Tirzepatide

    Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist studied in clinical research for its association with glycemic regulation and body-weight reduction.

    Read profile
    Weight Loss

    Retatrutide

    Retatrutide is an investigational triple-receptor agonist studied in clinical research for its simultaneous activity at the GIP, GLP-1, and glucagon receptors and its association with large body-weight and metabolic changes.

    Read profile
    Cytoprotective Peptide

    BPC-157

    BPC-157 is a synthetic pentadecapeptide derived from a sequence in gastric juice protein, studied in preclinical models for its association with angiogenesis, tissue-repair signaling, and cytoprotection.

    Read profile
    Growth Hormone Secretagogue

    CJC-1295

    CJC-1295 is a synthetic growth-hormone-releasing hormone (GHRH) analogue studied in preclinical and clinical research for its association with stimulated growth-hormone and IGF-1 release.

    Read profile
    Growth Hormone

    MK-677 (Ibutamoren)

    MK-677 (ibutamoren) is an orally active, non-peptide growth-hormone secretagogue and ghrelin-receptor agonist studied in clinical and preclinical research for its association with sustained, pulsatile growth-hormone and IGF-1 elevation.

    Read profile
    Mitochondrial-Targeted Peptide

    SS-31 (Elamipretide)

    SS-31 (elamipretide) is a mitochondria-targeting tetrapeptide studied for its selective association with the inner mitochondrial membrane lipid cardiolipin and its effects on mitochondrial bioenergetics in research models.

    Read profile
    Recovery

    Larazotide Acetate

    Larazotide acetate is a synthetic octapeptide studied in clinical and preclinical research as a tight-junction regulator that is associated with reduced intestinal permeability ('leaky gut').

    Read profile

    References

    1. Wilding JPH, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1). N Engl J Med. 2021.Source
    2. Jastreboff AM, et al. Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1). N Engl J Med. 2022.Source
    3. Jastreboff AM, et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity: A Phase 2 Trial. N Engl J Med. 2023.Source
    4. Lau DCW, et al. Once-weekly cagrilintide for weight management in people with overweight and obesity. Lancet. 2021.Source
    5. Falutz J, et al. Metabolic effects of a growth hormone-releasing factor in patients with HIV-associated lipodystrophy. N Engl J Med. 2007.Source
    6. U.S. FDA. EGRIFTA SV (tesamorelin) full prescribing information, 2024.Source
    7. U.S. FDA. FORZINITY (elamipretide) full prescribing information, 2025.Source
    8. U.S. FDA / DailyMed. VYLEESI (bremelanotide) prescribing information.Source
    9. Teichman SL, et al. Prolonged stimulation of growth hormone and IGF-I secretion by CJC-1295 in healthy adults. J Clin Endocrinol Metab. 2006.Source
    10. Imbimbo BP, et al. Growth hormone-releasing activity of hexarelin in humans: a dose-response study. Eur J Clin Pharmacol. 1994.Source
    11. Astrup A, et al. Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients. Lancet. 2008.Source
    12. Chapman IM, et al. Stimulation of the growth hormone–IGF-I axis by daily oral MK-677 in healthy elderly subjects. J Clin Endocrinol Metab. 1996.Source
    13. Dalton JT, et al. The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function. J Cachexia Sarcopenia Muscle. 2011.Source
    14. Karaa A, et al. Efficacy and safety of elamipretide in individuals with primary mitochondrial myopathy: the MMPOWER-3 randomized clinical trial. Neurology. 2023.Source
    15. Lee C, et al. MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. Nat Commun. 2021.Source
    16. Barnhart KF, et al. A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys. Sci Transl Med. 2011.Source
    17. Dahan A, et al. ARA 290, a nonerythropoietic peptide engineered from erythropoietin, improves metabolic control and neuropathic symptoms in patients with type 2 diabetes. Mol Med. 2015.Source
    18. Leffler DA, et al. Larazotide acetate for persistent symptoms of celiac disease despite a gluten-free diet. Gastroenterology. 2015.Source
    19. Naimi RM, et al. Glepaglutide, a novel long-acting GLP-2 analogue, for patients with short bowel syndrome. Lancet Gastroenterol Hepatol. 2019.Source
    20. Jayasena CN, et al. Kisspeptin-54 triggers egg maturation in women undergoing in vitro fertilization. J Clin Invest. 2014.Source
    21. Zhang C, et al. FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. Aging (Albany NY). 2020.Source
    22. Staresinic M, et al. Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon. J Orthop Res. 2003.Source
    23. Cerovecki T, et al. Pentadecapeptide BPC 157 improves ligament healing in the rat. J Orthop Res. 2010.Source

    Research Use Only

    For educational and laboratory-reference purposes only. This is a source-controlled index of historical study facts, not medical advice, a prescription, or an administration guide. The database includes approved drugs, non-peptide compounds, mixtures, and investigational entries; regulatory status is compound- and indication-specific. Research products are not necessarily approved, sterile, accurately labeled, or suitable for human use.